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| Benvenutti,Régis Carlos; Gomes,Denise B.; Zanchet,Barbara; Locateli,Gelvani; Vechia,Cristian Alex Dalla; Zanotelli Serpa,Patrícia; Lutinski,Junir; Rodrigues Junior,Sinval Adalberto; Schönell,Amanda Patrícia; Diel,Kriptsan Abdon Poletto; Miorando,Daniela; Ernetti,Jackeline; Alves,Bianca de Oliveira; Zilli,Gabriela Adriany Lisboa; Banzato,Thais Petrochelli; Ruiz,Ana Lúcia Tasca Gois; Vidal Gutiérrez,Max; Vilegas,Wagner; Roman Junior,Walter Antônio. |
| Abstract Natural products, especially phytochemicals, have been extensively studies and have exhibited important antiproliferative effects. The American native species Urera baccifera (L.) Gaudich. ex Wedd. (Urticaceae) is widely distributed in Brazil, where it is known as urtiga-vermelha or urtigão. The leaves are popularly used as anti-inflammatory, antirheumatic and in the treatment of gastric disorders. However, the antiproliferative potential of this plant against human tumor cells remain to be elucidated. In this study, we evaluated the antiproliferative effects of U. baccifera leaves extracts and fractions against a panel of human tumor cell lines in vitro besides a chemical evaluation of the most active sample by mass spectrometry (ESI-IT-MSn). The... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antitumor agents; Medicinal plants; Chemical analysis. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132019000100412 |
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